The hippocampus (HC) is crucial for transforming our experiences into long-lasting memories. The HC is among the brain areas most sensitive to adverse developmental events across the lifespan. The HC is not a homogeneous structure, but rather is composed of cytoarchitectonically and functionally distinct subfields. The new frontiers in understanding the neural underpinnings of changes in memory across the lifespan are a focus on changes in the connectivity and in the joint contributions of HC subfields to memory. Advances in magnetic resonance imaging (MRI) now enable us to assess lifespan changes in HC networks using high-resolution MRI and (2) to identify concomitant changes in computations supported by the HC network. Our lab pursues these goals with research including children, adults, and older adult samples, using magnetic resonance imaging and/or behavioral methods.